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Ischemic optic neuropathies
In HaCaT model, quercetin treatment was associated with decreased secretion of CCL17 and CCL22 secretion, potentially through modulation of the TLR2/6 and MAPK signaling pathways (Hou et al., 2019)
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Positioning of ThDP-dependent 2-oxo acid dehydrogenase complexes at the intersections of major pathways of central metabolism and transcriptional regulation endows these systems with a functional role of signaling hubs, regulating multiple cellular processes, such as intracellular redox status, growth, protein signaling, and calcium homeostasis (5052)